You will likely have lots of people on here responding with 'oh no, don't say anything!'. It depends a lot on what sort of relationship you have with your daughter as to whether or not you can broach the subject. If you have always had a very open mother-and-daughter relationship, always talked about everything, then it might be possible to say something - and you will know her well enough to know how to approach the subject gently. But please bear in mind that it may not be intentional that she is 'leaving it too late'. It could be that despite all their efforts, she has so far been unable to conceive. Or maybe she has conceived several times and then the pregnancy has ended early on. It could be a very, very delicate subject.
Do you know that she even wants children? There's always that possibility!
If, on the other hand, it is a conscious decision to delay starting a family, I'm sure she is aware of the clock ticking and won't need you to remind her .
I do sympathise - it's so hard being a 'grandparent in waiting', isn't it? Only you know if you can bring up this subject with your daughter. But be aware, it is a minefield! Good luck.