I have IBS-M, was diagnosed in my 60s, I’m sure it was caused/exacerbated by stress at work. I was prescribed Mebeverin at first but that didn’t help at all, then a different GP in the surgery prescribed Buscopan which did/does help. I tried various changes in diet, none of them made any real difference. Because of the stress, I was diagnosed with anxiety and depression, and I eventually ended up going off work on long term sick, went through a lengthy absence policy procedure and took early retirement (three years before I was due my state pension). That was five years ago. My IBS is fairly well controlled nowadays, still have the occasional bout, and usually have no idea what has triggered it. I eat lots of veg, not much fruit. Normal mixed diet otherwise.
Like Happy I also have asthma, that was diagnosed in my 30s, and is (usually) very well controlled by medication.
In light of our current weather.......
sticky labels on apples - remove before washing!