I would agree that you need to separate out your anxieties.
Of course you don't like the idea of them moving a long distance.
I have a feeling that in the UK our media disparage the US in order to make us feel better. I hold no brief for it, but have known, over my lifetime, many Americans and people who have moved there (I live in an area that still has a US base). There are many things about America that I admire and respect, as well as things that are worse than the UK.
There are plenty of excellent schools in the US - I suspect that the schools are one small factor in a lot of other things. One friend did a 'job swap' and thought highly of the year's US schooling that her children had.
I hope your SiL is caring and thoughtful - in which case he will have considered the issue of healthcare insurance, and especially checked the mental health clauses.
I think your grandchildren will benefit from seeing a different culture, and especially connecting with the American side of their family and its history.
I think you need to deal with your anxieties yourself, and maybe some of the US grans who come here can help with that.If you can, put some savings by so you can travel there quickly if needed.
Good luck.
To go through chemo therapy or choose not to?
Army horses loose on London streets