Having had proper flu just once, I certainly would. I was much younger and perfectly fit, but it still knocked my stuffing right out for over 3 weeks, even after I felt better.
Plus (look away now if squeamish!) all the coughing weakened the relevant muscles so much, that for quite a while afterwards, every time I coughed or sneezed, I wet myself* and farted at the same time.
*a bit, not a deluge, and just as well when I was at work.
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