St John's Wort has been shown to be as effective as anti-depressants in some people, as per article in the BMJ a couple of years back. However, it is a strong herb that can interfere with some other drugs (many drugs are based on natural herbs, aspirin from birch bark, digitalis from fox-gloves, etc). So to say herbal remedies have no effect is silly.
The main problem with St John's wort is sensitivity to light- so extra care should be taken with wearing sun-glasses and not sunbathing, avoiding strong sun light.
Passiflora, hops, valerian, rosemary, melissa, verbena and many more, are known for a calming effect without side-effects- so why not. But yes, always check with pharmacists for reaction with other drugs.
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- and it is complementary medicine 
