I have been taking tramadol for several years. I have osteo and rheumatoid arthritis,plus fibromyalgia and can't take NSAIDs as they give me awful stomach ache and make me sick. I got on fine with tramadol from the start. I usually take 2 in the morning,2 in the evening, and sometimes 2 in the afternoon,depending on my pain levels. They have certainly helped me manage better. But,I will say that they ARE addictive. If I have forgotten to take my morning dose,which has happened a few times if I have got up and had to go out in a bit of a rush,I feel ABSOLUTELY AWFUL within a couple of hours. Not just physically,but mentally. So they do affect your mind,as well as your body. My GP was not overly concerned when I asked about being addicted to them. He said as long as they were making me feel better and in less pain,not to worry,as I'm not even taking the maximum daily dose,let alone exceeding it.