When DH was first put on chemotherapy with all thassociated drugs I did start reading the leaflets. I found that a whole lot of them shouldn't be taken together but took it that treating the cancer was more important than any contraindications.
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It's a very mild opiate, which suppress coughing and what makes it effective, so any side effects would be commensurate with that group of drugs. In all the years I worked in hospitals and pharmacies, I never heard of anyone having a bad reaction.