Puddles you don't say whether your doctor has prescribed Thyroxine or not. When I was first diagnosed with an under active thryroid, probably getting on for 20 or so ago, the doctor I saw at the time told me I was borderline and didn't need to take anything, I was feeling terrible back then just simple tasks were a supreme effort. Shortly afterwards I saw another doctor in the same practice who told me I most defintely should be taking it. I think I started off on less than 100mcg but now take 150 and was told that according to my latest blood test this should be upped to 175. I saw an endcronologists quite a few years ago who advised that high doseages of Throxine can compromise bone density and as my mother had Osteoporosis towards the end of her life, I was reluctant to take a very high dose so with my doctor's agreement I'm sticking to 150, which is quite high anyway. I have never found Thyroxine a silver bullet as far as depleted energy levels are concerned, but I have to admit that I also have peri menopausal symptoms which also contribute to how I feel. I have often read about "Armour" derived from pigs which is prescribed in America in some cases, when Hillary Clinton made her medical records available, I saw that she was on that. It's thought that it's more effective in treating the symptoms of an under active thyroid, but unfortunately not approved by NICE in the UK, it's much more expensive to produce than synthetic Thyroxine. You can google doctors, who I think will prescribe Armour privately in the UK, I believe there was one at Northwick Park Hospital the last time I looked, I think they tend to be a bit circumspect about doing so. From the various threads on GN and other forums on under active thryroid its seems to be a bit of a lottery as to how effective conventional Throxine is in treating the condition as it seems that some do not absorb it well. One of the posters here on GN advised it was better taken at night and I have been doing that for a while. Good luck in your quest.