I've been taking Omeprazole (20mg) for about 5 years, it was prescribed to protect my stomach from the Prednisalone steroids I take for Asthma. I never really had any problems with acid reflux, only occasionally, and that could be attributed to something I'd eaten. I sometimes get mild stomach cramps but I generally blame that on my IBS-D.
I haven't had a review of any of my medication for over two years, I just get repeat prescriptions. Prior to the pandemic I was told to very gradually reduce the Prednisalone dosage from 20mg, but I can't get below 15mg (even that doesn't work so well now) without becoming a 'puffing billy'!