Hi Dr Rosemary, I had a total hysterectomy at 42 due to endometriosis and was immediately given an oestrogen only HRT estradiol. It worked for years extremely well until my Gp put me under pressure to come off it last year. Now all the menopause symptoms have returned with bad night sweats, horrible hot flushes, mood swings and little energy. I'm now 60 and coming off HRT coincided with a worsening auto immune disease, which I've had for over 30 years, psoriatic arthritis, which then started in my spine, neck and lower back, knees, hands etc. So I'm already struggling to cope with work, chronic fatigue and constant pain. The hospital doctor indicated that coming off HRT may not be a good idea given the increased risk of osteoporosis together with my degenerative spinal disease. Is there any reason we can't stay on a low dose of HRT if it's working? Or is there an effective alternative. I've been looking at bio identical natural HRT but don't know how effective this would be? Any advice would be much appreciated.