35/F/MO I registered to this website to share and add my recent experience. I too woke up 3 days ago with rusty orange hands. Mine are mostly on tops of my hands also on my palms, wrists, finger tips, nail beds, and making its way up my arms. Right hand has it worst. I had spotting on my lower back right above my butt crack area, and a weird strip on my leg. It does not come off unless you scrub extremely hard but doesn't come all the way off. Mine looks yellow sometimes when it comes off but mostly rusty orange. I have not had the covid vaccine. I have used baby wipes my entire life! Parents choice brand. I just got my blood drawn today to test for hypothyroidism. I do not consume a lot of orange veggies or fruits. Rarely eat spinich unless I eat Subway. I mostly eat beef, jalapenos, cheese, flour tortillas, bread, garlic powder, drink soda. I do have an issue with stink bugs getting in my house. The kind that smell like cilantro. I have been stressed/depressed/anxiety for the past 5 years but this year has been the worst. My PCP said she doesn't believe it has to do with my liver because my eyes aren't yellow. This is crazy! I'm glad to know I'm not alone!