I have 8 granddaughters and 1 grandson. He is in the middle of the girls. Growing up he had to endure having his nails painted and his head covered in hair clips but at 17 now, it doesn't appear to have done him any lasting harm.
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I have 3 DD's and 2 DS's and have always found a difference between the genders.
There always seems to be some sort of drama going on with girls whereas boys just seem to take life as it comes. If girls fall out, which happens with monotonous regularity, it is tearfully, all-consuming until they are friends again. Boys wouldn't be so bothered. They are much more laid back. Boys also like a cuddle with Granny for much longer than the girls.
You enjoy him. Baby and toddler toys are for either gender but as he grows up you may have to learn the offside rule. Good luck with that!