I would first say to them 'why are you being mean to me'? Depending on the answer tell them what you think and that no one will enjoy their company if they can't be kind. They are at the 'testing boundaries' age and need to be told.
Whether you tell your daughter really depends on what she is like.
Is she likely to just defend them? If so, you will just feel worse and the boys will have been emboldened.
If she is likely to 'have a word' with them about it, then telling her might be best.
If you go to her first though, they will just see you as someone who tells tales behind their backs (a cardinal sin so far as children are concerned).
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