This is a good question and something that always worries me since I bought a new F/F which you cannot isolate the fridge on (my previous model enabled you to isolate the freezer and leave the fridge working as I need to keep my supplies of Insulin cool) when I lived in France my neighbour asked me to turn it off (she was looking after my house, and having read about fires caused by those appliances felt better if it was completely off,,,,,so I did and she stored my insulin in her garage fridge !) better to be safe than sorry ...I contacted Hoover (my new F/F/ supplier who told me there is a 'holiday mode' that can be enabled ...I have yet to look online at the manual as the print in the one that came with it is too small for me to read ! If I think it is ok I will leave it on, but if not, I will have to find someone to store my insulin in theirs ...............still worries me though, especially after Grenfell and now that I live in a block of retirement flats (no cladding) but it was ok for this weekend when I went away for three days, but have got lots of holidays booked (all cancelled from 2019 or 2020) so I need to look hard at the options ! I would I think prefer to switch it off and then have a good shop to re fill it when I get back ................