Covid vaccination trials

Just a bit of news.

Oxford as we know has restarted and is in late stage 3. So with luck we may know before Christmas.

The reason we hear so much about Oxford is that it is entirely British and we are very likely to have that vaccine.

The Glaxo one, part of which is being developed in the U.K. but American, and which my daughter is working on is different from the Oxford because they are attaching an adjunct onto the protein (belt and braces). That is to boost the immune system, because at the moment anti-bodies only seem to be giving us about 4 months or so immunity. The vaccine will hopefully be a yearly one.
Glaxo is just started stage 3 so is a bit behind.
Excuse my explanation any scientists amongst you, as you might gather I am not a scientist, and trying to remember what was daughter was saying.

Good Evening; Here's a somewhat different "take" on the subject, as appeared in one of our newspapers this weekend!

Quote; "At this point it's worth recounting that Victoria enacted voluntary euthanasia laws late last year and in the first 12 months of operation at least 124 people have availed themselves of assisted dying. Presumably, if any people who have won approval to end their lives test positive, they too will be listed as coronavirus fatalities."

So there you are! You'll be a statistic even beyond the grave (or crem.)
OoRoo

covid19vaccinetrial.co.uk/trial-resumes#

Here's some good news.

Thanks NannyB2604

Here's an example of the damage bad reporting can do. DH and I went to visit a new small business near us this morning, a very nice van selling fresh sandwiches near a local tourist spot. Lovely chat with the young man running it. He told us he was going to put all his plans for expanding his business on hold because now that the vaccine trials were stopped we were going to be in this situation for years.

He got treated to the Alegrias vaccine pep talk....

We'll said Alegrias!

I thought the Oxford vaccine is using tried and tested methods. The other two major ones (Moderna and Pfizer/Biontech) are using a totally new untried approach, an RNA vaccine. Well this is what I've understood from the youtube videos by Dr John Campbell.

I love what your daughter says WWM2! It confirms what I thought, that the standards of media coverage during this crisis have been abysmal.

For example, this morning, BBC Scotland are saying that there were cases in all mainland Health Boards yesterday. NS mentioned it at her briefing yesterday. The implication is that its all out of control. But there were cases in all health boards on September 6th, September 1st, August 30th and August 27th, and before that. Why didn't they mention it then?

I'm going to shut up now as well

Just heard from DD

She says it is media hype.

This is apparently the second time it has been halted and is just routine. Not sure why it’s made the news now.?‍♀️

So I got it sort of wrong as well!! I shall shut up in future.

growstuff

I think one of the problems is that only a couple of months ago, the media was headlining the possibility of Oxford/AZ having a million doses by September.

uk.reuters.com/article/us-health-coronavirus-oxford-vaccine-res-idUKKCN24L1TW

There was a thread on GN about it and people were getting excited. Those of us who pointed out the use of words like "if" and "would" were accused of being negative.

I'm sure that the July announcement was more about boosting AZ's shares.

Now the Oxford trial has encountered a problem, people are going to the opposite extreme and I expect the anti-vaxxers will jump in it.

We jump from one extreme to the other.

The truth is that it would be surprising if there weren't a few problems. There isn't going to be a vaccine for a while yet and nobody can rely on one as a "get out card". We have to find another realistic way of dealing with Covid until then.

Exactly!

Who is aware that Cambridge or Imperial College or Sheffield or Manchester, Edinburgh, Southampton, Surrey, Glasgow, Belfast etc etc are all beavering away?

Daughter is saying everything crossed for an early success but realistically it is a while off. She is just a cog in the massive wheel that is searching for a vaccine.

Meanwhile there is a huge amount of research and a good deal of success in finding treatments for covid.

I think one of the problems is that only a couple of months ago, the media was headlining the possibility of Oxford/AZ having a million doses by September.

uk.reuters.com/article/us-health-coronavirus-oxford-vaccine-res-idUKKCN24L1TW

There was a thread on GN about it and people were getting excited. Those of us who pointed out the use of words like "if" and "would" were accused of being negative.

I'm sure that the July announcement was more about boosting AZ's shares.

Now the Oxford trial has encountered a problem, people are going to the opposite extreme and I expect the anti-vaxxers will jump in it.

We jump from one extreme to the other.

The truth is that it would be surprising if there weren't a few problems. There isn't going to be a vaccine for a while yet and nobody can rely on one as a "get out card". We have to find another realistic way of dealing with Covid until then.

We're on the same page WWM2

Alegrias

Thanks for the clarification WWM2

I'm very concerned generally that there are vaccine-sceptics out there who will jump on any perceived negative about vaccines and trials. So if a trial is "stopped" the conclusion must be that it was dangerous. Then if/when it restarts then they must be disregarding safety.

Other vaccines are based on proven technology; hence the Oxford one is unproven and we should avoid it at all costs, forever.

"Other trials are taking place that are proven more reliable" - so the Oxford trial isn't reliable?

Obviously I'm using these as examples and its not what I think, but we have to be so careful about the messaging around these things.

Oh no!! I along with everyone in the entire world hope that we get a reliable vaccine soon and I don’t care which institution develops it.

But they are all working and cooperating towards just that.

Talking about reliability. Apparently there are tried and tested and reliable technologies always used in the development of vaccines.

Pharmaceuticals have used these for decades. However they do know if other possible ways forward which are as yet not tried and tested so their reliability isn’t proven.

Oxford and AstraZeneca have chosen this with the hope presumably that it proves successful.

The whole world and his wife in the pharma industries in conjunction with universities world wide are working on treatment as well as vaccine for covid. ?

BlueBelle
medications that will lessen the severity Have you seen this?
www.imperial.nhs.uk/about-us/news/steroid-found-to-improve-survival-of-critically-ill-covid-19-patients

Thanks for the clarification WWM2

I'm very concerned generally that there are vaccine-sceptics out there who will jump on any perceived negative about vaccines and trials. So if a trial is "stopped" the conclusion must be that it was dangerous. Then if/when it restarts then they must be disregarding safety.

Other vaccines are based on proven technology; hence the Oxford one is unproven and we should avoid it at all costs, forever.

"Other trials are taking place that are proven more reliable" - so the Oxford trial isn't reliable?

Obviously I'm using these as examples and its not what I think, but we have to be so careful about the messaging around these things.

Jess20 - I really don’t think the alternative to an individual volunteering for trials here, is to trial vaccines on people in third world countries who have less of a safety net.

One thing doesn’t follow from the other!

Alegrias

The trial hasn't been stopped.

It has been paused because one of the 17,000 people in the trial has become ill. They don't know if it has anything to do with the vaccine but are being super cautious. This is normal for vaccine trials. A decision on starting again is due in a few days.

It's completely wrong to say other trials are taking place that are proven more reluable, and it's dangerous misinformation.

Read the article, not the headline.

My daughter -a genetic engineer is in contact with the Oxford group and knows what she is talking about.

I am sorry I should have made that clear in my post, as yes if I had said these things as a matter of opinion of course I would have been wrong. And I accept that the trials have been paused, my language was incorrect. But if you had read what I said I did say that I hoped it was just temporary.

Other trials being tested are based on different technologies, that is a fact.

They are being carried out by other institutions and pharmaceuticals and the technology is different. I can’t go into detail.

The trial hasn't been stopped.

It has been paused because one of the 17,000 people in the trial has become ill. They don't know if it has anything to do with the vaccine but are being super cautious. This is normal for vaccine trials. A decision on starting again is due in a few days.

It's completely wrong to say other trials are taking place that are proven more reluable, and it's dangerous misinformation.

Read the article, not the headline.

I see that the Oxford trial has been stopped as someone has fallen ill.

My daughter explained to me some time ago that the Oxford technology is untried and untested and in her opinion the vaccine trials being carried out by other people are more likely to succeed. These are based on technology that has proven its reliability.

I hope that Oxford is just a blip, but at least we know that other trials are taking place that are proven more reliable.

I am new to this, people seem to be aware of the present troubles, I am of a like mind.
So I can do my bit incase people don't know there's an American utube and Web site run by Intensive Care Docs in California I can't recommend strongly enough - Medcram.com especially number 59, if you look you will see why cheers.

I can't see where anyone called you selfish, BlueBelle, maybe I missed it. People must of course be free to make up their own minds about having a vaccine or not. But they must consider the facts, not hearsay.

We need to nip this idea in the bud, that someone is leaving a slot for other people if they don't have the vaccine.

Vaccines not only protect the person who is being vaccinated, they drive up the immunity of the whole population and reduce the likelihood of a disease spreading out of control. Read AGAA4’s post above to understand how people who have the vaccine are helping those who cannot have it. I would have thought that someone who worked in the NHS and understood how pharmaceuticals worked would have known that already.

I m not being selfish who ever said that as I ve no intention of using the vaccine so it ll keep one slot free for someone who does want to have it so I m being very unselfish
So far almost everything this Gov has done (even that done by scientists advice) has had to be reversed so I m happy, more than happy to play a wait and see game

I m much more interested in medications that will lessen the severity, that is well worth waiting for

I'm on the Oxford University Covid-19 vaccine trial (the Sheffield site). A thorough questioning of my medical history, blood tests then an injection - either the trial vaccine or the meningitis vaccine routinely given to teenagers. I now have to take a Covid test once a week until I get the booster jab after 6 weeks. Luckily no side effects from the injection and I'm now one negative test down. Fingers crossed the trial is successful and we can start getting back to a normal life.

No Covid vaccine before winter of 2021, warns Chief Medical Officer

Chris Whitty says it could take another year before a safe vaccine is developed and ready for widespread distribution.

www.telegraph.co.uk/news/2020/08/22/no-covid-vaccine-winter-2021-warns-chief-medical-officer/

Omg! I just looked up translation in Google translate (see above) “Who can read this. I love Vladimir Putin”. NOT!!

Personally I would steer well clear of being a guinea pig. It takes years to develop vaccines and the speed this is progressing is not only suspect but extremely worrying. There is no way it can be deemed as safe in any way, even though they will tell us it is. You could be doing yourself irreparable harm. Please don't do it.