I wouldn't venture any sort of opinion, as every circumstance is different.
My "best" friend was estranged by her eldest daughter over 30 years ago.
It started when the girl started taking drugs, she went to her GP for help with this, but, unfortunately, the GP just prescribed anti-depressants and offered no help with the drug problem.
The combination of drugs and medication sent things into freefall.
She went to counsellors who seemed to encourage her to think of herself as some sort of perpetual victim. To be fair to them, though, the girl lied about everything. Every few months she was accusing some man or another of raping her, and then, a few weeks later, confessing it wasn't true.
Since then, her life has been a car crash - her three children were taken into foster care, and her life has been one of ever harder drugs, violent men, and evictions.
She has estranged her mother, siblings, previous friends, extended family, and her own children. Her father died during the early stages.
I was very close to this girl, because of my friendship with her mum, and the fact that she and my daughter were best friends for years. She used to call me "her second mum".
Because of this, I have always kept lines of communications open with her (her mother, my friend knows this and is happy about it).
Periodically, she contacts me, saying she's in rehab, and wants to reconnect with her mum.
We talk it through, I have suggested a "starting point" text or letter, and she agrees. She wants to make the first move, without actually talking to anyone, as she says she feels ashamed of all she's done.
All good - but only when she's in some sort of rehab.
Unfortunately, rehab then discharge her, she returns back to her local area, and the drugs and lifestyle have a bigger pull than her family.
My friend, happily, has kept contact with her grandchildren, and they have a great relationship. But, she would like her daughter back, although has given up on it really.
There's nothing I can say or do, if AC's wander down a "car crash life", it's just impossible to solve or advise on.
Drugs can be an unbeatable force.
My friend doesn't dwell on it, she has a great life, with friends and her family, and we rarely speak about it, but it's very sad.?