MGUS Are there any symptoms that i should look for?

idavidi I have MGUS too, it's rare (3-5% of the population but more common as people age). The acronym means Monoclonal Gammopathy of Uncertain Significance although research is now beginning to unravel the condition and discover its significance.

The medical profession say there are no symptoms but its not difficult to find patient forums which make it clear that there are symptoms such as neuropathy, fatigue, joint pain, kidney disease. There are a number of active patient groups on Facebook from which I've learnt a lot.

MGUS progresses to multiple myeloma at the low rate of 1 per cent per year but that is cumulative, ie, 10 per cent after 10 years. It is known that all multiple myeloma sufferers have MGUS first so the diagnosis is alarming. Hence, regular monitoring - blood tests every 3 months for 2 years, after that they assume you are stable and the condition won't progress. MGUS is linked to autoimmune conditions like rheumatoid arthritis and and is a malfunction of the immune system where a protein clones itself rather than producing a normal antibody.

It's frightening to be diagnosed with something rare and the name of this condition, never mind the acronym, causes a lot of anxiety.

The poster presents apologies for the difficulty that he presented to you.

It's a protein in the blood that usually causes no problem. I agree posters should afford the rest of us the courtesy of stating the meaning of acronyms, otherwise it comes over as a sort of superiority thing even if not intended to be.

I could not agree more- it is not a recognised acronym.

My thoughts precisely BlueBelle!
If you want to discuss a subject it's courteous to introduce it clearly.

I do wish people on here would at least once in their original post state what the acronyms stand for
Now off for coffee with my friend google

Update:
I Went to doctor for my next tests and the results came out positive. I have MGUS. Doctor has suggested me to rest for a day and start my diagnoses tomorrow

After several tests they told my husband he had mgus but found out later that he has Amyloidosis and hasto go to the Royal Free hospital in London on a regular basis now

Tests are vital in the search for any abnormalities in the blood. There aren't usually any significant symptoms but extensive testing will rule anything out.
It's one of those things that's only detected through routine tests.