Yes, I was told to take my thyroxine tabs first thing in the morning, with just water at least 30 mins before eating or drinking anything with caffeine. I place these tabs into a small container by my bed with my drinking mug, and usually take them when I first wake up for the morning, then have a good half an hour relax in bed before I get up for brekkie.
There are a lot of meds. that do not work together, and a chat to a pharmacist to review exactly what you are taking and how, will set you in the right direction.
I also take Vit C twice daily, and have to ensure that at least four hours have elapsed from taking my thyroxine tabs before taking one of these.
I also have a once a week Vit C tab which needs to be taken with water well before eating. This does cause me some confusion as to how to work this in with Levothyroxine. So, I now take that when I do one of loo visits during the night.
How and when we take our medication is as important as what it is.