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Omeprazole vs Lansoprozole

(45 Posts)
Esspee Wed 18-May-22 14:52:50

Thanks Fennel. I'm on a boat and the sun is making reading difficult.

Esspee Wed 18-May-22 14:49:36

I had a thread on this subject just last week quoting from the most recent paper which concluded there was a definite association.
I was concerned that many self medicate without understanding the risks.

sandelf Wed 18-May-22 14:25:05

Hi Nikita80 I have a 'rolling hiatus hernia'. Did research and found the symptoms are worsened by stooping posture and anything other than being upright after a meal. Dr advised Omep - but as a thin white women I did not want to increase the risk of bone loss etc. So took to self help - better posture (I don't always manage but hey ho) and a teaspoon of Glutamine power in cold water before food in the morning. Glutamine is a protein that is particularly needed by the GI tract lining - and it is easy not to get enough. Just my thoughts - all the best.

Hetty58 Wed 18-May-22 14:16:24

GrannyLaine, spot on - adjust your diet. It's bonkers using medication to relieve the consequences of a 'bad' diet. Daily probiotics and/or Kefir may help.

Nikita80 Wed 18-May-22 14:08:23

Thank you for all your feedback. Yes there both prescription only. I don't use the GP, I prefer online pharmacy. The online doctor at The Family Chemist gives me advice and I find it more efficient and reliable, but ultimately it depends on me. I think after careful consideration and reading comments I will be going ahead omeprazole.

In regards to my diet, I am going to start eating more healthy and cutting down on certain foods that cause me to have heartburn etc. I think hopefully both together be more effective. Stopping smoking has helped but my diet became poor as I have other cravings so its balancing it all out I suppose.

vegansrock Tue 17-May-22 16:31:23

They are both associated with inflammatory bowel diseases such as IBS and colitis.

Fennel Tue 17-May-22 16:28:29

A recent thread relevant to this on gransnet:
www.gransnet.com/forums/health/1310212-Alzheimer-s-linked-with-PPI-use

Audi10 Tue 17-May-22 16:09:56

Hi Nikita I have tried both of those given to me by my GP I stopped both due to reading about Alzheimer’s as I had a very close family member with it! And I changed my diet completely the reflux has not gone but not as bad as was! Also I know that many meds increase the chances of certain illnesses over the years, but for me I wanted to try going down the natural way after reading about it! And I’m happy that my diet now is reducing the effects!I wouldn’t advise anyone ever to stop taking any meds it’s down to each individual to talk to their dr or consultant if they are concerned

GrannyLaine Tue 17-May-22 16:02:05

Nikita80 would it perhaps be better to look at your diet first?

GrannyLaine Tue 17-May-22 16:00:14

Esspee

Both are associated with increased risk of Alzheimer’s.

I would be looking for another solution.

What is the extent of the increased risk*Esspee*? Many on this site will be taking PPIs and without context, that isn't helpful information.

Casdon Tue 17-May-22 15:22:12

Isn’t Lansaprazole prescription only, so your GP would need to decide with you which was best?

Marydoll Tue 17-May-22 15:17:14

OakDryad

A clinical study concluded: There is no significant difference in the clinical effectiveness of omeprazole and lansoprazole in relieving symptoms of heartburn and regurgitation. However, omeprazole is more effective in reducing gastric acidity than lansoprazole.

jmrionline.com/jmri/article/view/204

I was on Omeprazole, but it was totally innefective, so my GP changed my prescription to Lansoprazole, which did help.

Something which does work for me, is eating probiotic yoghurts first thing.

OakDryad Tue 17-May-22 15:09:07

A clinical study concluded: There is no significant difference in the clinical effectiveness of omeprazole and lansoprazole in relieving symptoms of heartburn and regurgitation. However, omeprazole is more effective in reducing gastric acidity than lansoprazole.

jmrionline.com/jmri/article/view/204

Jaxjacky Tue 17-May-22 14:18:59

So can other commonly used drugs Esspee as always, it’s quantifying the personal risk v benefit.

Esspee Tue 17-May-22 13:44:08

Both are associated with increased risk of Alzheimer’s.

I would be looking for another solution.

annodomini Tue 17-May-22 13:39:06

Omeprazole has worked well for me. It saved me from the effects of stomach acid on my vocal chords, though if I try to sing up the scale, my voice cracks at 'soh' which is no handicap as I was never a great singer.

Athrawes Tue 17-May-22 12:26:11

I take Lansoprazole on a daily basis but initially I had awful itching from it. Hopefully I'll come off it soon as I'm beginning to rattle as I take quite a few tablets at various times and am not sure what good Lansoprazole's actually doing. I'm not due for a consultation for a bit though.

Keeleklogger Tue 17-May-22 12:19:32

I have to take Omeprazole daily, I have to side effects at all. It works for me. It’s on prescription

midgey Tue 17-May-22 11:44:31

Omeprazole made me feel awful, lansoprazole seems okay. But I think they are both on prescription only in the UK.

Nikita80 Tue 17-May-22 11:41:43

Hi Everyone!
So I have asked a clinician but still seem rather confused, I suffer bad acid reflux and get burning sensations in my chest. My diet is poor and I know that. But since I have stopped smoking seems to be worse. Which one do you recommend I purchase, price is the same so that doesn't matter. I am just thinking about which one will have better results.