I too am intolerant to SSR’s I tried sertraline, and mertazapine. I was on it for six months and had diarrhoea the whole time. Eventually my GP sent me for a colposcopy, ( a camera inserted into your back passage to your bowel.) The result was fine. I asked my GP if it could be the anti depressant that I was on? He told me the only way he could tell was if I stopped taking it gradually, which I did.over a couple of months. I was fine for about three weeks, then the anxiety, panic attacks, depression all started again. But, the diarrhoea stopped. So, it was the tablets. I went to see another GP out of hours, as no appointments at mine. He put me on an an antidepressant from the SNRI’s group I have now been on this for about two and a half years. This group suits me, but it may not suit you? Good luck on your journey. And so many people suffer with mental illness.