I have widespread OE, including knees, I cope with exercises and either Voltarol or, especially on the heat, the cold freeze gel.
Is he using a stick? It does help.
I do sometimes take ibuprofen as paracetamol was useless. (Though told not too)
Have you thought about physio? Especially if they use laser or other treatments rather than just exercise alone.
He could ask for a pain clinic referral, but I found them to be little help, despite two referrals.
Massage can help, as can hydrotherapy.
Good luck, at 80 he’s done well to avoid OR for so long. Both DH and I “acquired” this condition in mid 60’s. Both good walkers prior to this.