With regard to your first question, if you are struggling to find somewhere to place these items in your bedroom, then ask yourself if they are really needed? If they are, then I suggest you deal with them now rather than leave them lying around in the bedroom (or elsewhere). If they are not essential to you, then pass them on to someone who could use them.
As to the loft, I suggest you begin clearing it gradually whilst you are fit and able to do so, otherwise it’s going to be a problem for whoever is tasked with clearing your house once you are gone or living elsewhere. Tackle one box at a time so that you don’t become overwhelmed, and ask yourself the same questions as you would about the things in your bedroom, ie, do you really need them enough to keep them stored.
Although we have a loft, there is nothing in it apart from the water tanks. We made a joint decision not to use it for storage.
When we bought the house there was a child’s bed, an old door and a piece of carpet up there, but we got rid of those almost straight away - a bit tricky trying to manoeuvre them out of the hatch, (which probably reinforced our choice not to store anything of our own there), but managed in the end. I wouldn’t like to be trying to move them now, we were more agile then.