Over 50.... beginning the Menopause.. June 2022

I had an early menopause at 39 (my periods stopped - thought I was pregnant). Was on HRT for 10 years to prevent things like heart disease. I had mild hot flushes but nothing else. Never had HRT since nor any particular symptoms though now at 66 my eyebrows are disappearing and I don't have to shave or wax my legs - result!!

A lot of women are on HRT for life. The health benefits for me are overwhelming but everyone is different.

I don’t understand where Setraline comes in. It’s an antidepressant, nothing to do with HRT. Perhaps you could fill in the missing bits in your post to make your story clear.