NotSpaghetti
^There is some evidence that when to take blood pressure medications (such as Perindopril) - morning or night, might vary according to ones own body clock.^
This question is actually asking about the new evidence and research papers that have looked at circadian rhythms and optimum time to take BP drugs.
I know that they are traditionally taken in the morning but was told that this is only because there is better compliance in the morning than at night.
(There are studies about compliance).
Please can you take a look again at this as I hoped you would be able to more easily digest the academic evidence.
As I said, I want to take them at the optimum time for me.
Thank you
Hi @Notspaghetti, in terms of the circadian rhythms, these are essentially caused by a release of hormones in the morning by the hypothalamus (a region of the brain) . These then trigger the feeling of waking and help you feel ready for the day. The rhythm that studies refer to is when that release occurs naturally, a bit like your own internal body clock. This rhythm can be changed, but it takes a few days, hence the term Jet Lag.
For some medications, it is best to try and time them with this phase of hormone release so that the effect of the medication is occurring as the normal release of Hormones starts to take effect. For Perindopril, as long as its taken at some point in the morning, it will be okay, as the time of action is quite long, so it will help throughout the waking part of the day.
Hope this helps .