I think she has been asked that question, way back in 2003 and by none other than Judy of "Richard & Judy" fame:
Before long, the Monica Lewinsky question popped up (Judy thought that Mrs Clinton should have left Bill, as she bravely pointed out). "Well, it should have remained private and personal but it was forced into the public for partisan political purposes which I found deplorable," she said.
And marriage? "Every marriage is a mystery to me, even the one I'm in. So I'm no expert on it. At the end of the day, you know, love does not happen between two perfect people as much as we would wish."
And Google tells me that she gave exactly the same response later that day in an interview on the radio.
Anyway, I'd ask her how she copes with getting older and still working as hard as she does.