Actually my advice is a little different - I see this from the viewpoint of the oldest daughter because she is relying on you - you are part of the structure that she has put in place to enable her immediate family's life to run smoothly. You have agreed to be part of that support system so unless you have a e-negotiation of that 'contract' you are obligated to continue. As far as your youngest daughter is concerned, she has moved into a situation which she already knows exists, I agree that she does have needs and that your wish to help her which is admirable should be satisfied, but what length of notice has she given you of her request to get you to change your routine? And your older daughter is correct when he says that the appointment can be changed. I work in the counselling field and I know that people who present for this type of support are often all over the place and do themselves cancel, and re-arrange at the drop of a hat. We are used to this. I suggest you talk with your youngest DD and tell her your time availability, promise her something you can honour such as regular slots of time that don't conflict with your commitments to your eldest daughter, and at the same time tell your eldest daughter that you are entering into this arrangement, so that she can't call on you for emergencies during those times. When you downsize your eldest daughter will have to make new arrangements anyway as it may not be convenient for you to do all the school deliveries/collections. This is all about you creating boundaries in the interests of letting each one of your daughters know that you care for them all, but you do of course need time for yourself and while you may choose to think of time with your grandchildren as fulfilling that for you, you will become tired, so try to plug in something more relaxing - a book club, a walking group, etc. Good luck. You love them all, but like most siblings, they are competitive and make judgements about each other that you as mum don't.