My Son in Law is totally shielding at present due to his medical problems and the medications he is on. So, he is totally isolated in what was, their bedroom, fortunately with en-suite as hospital told him he must have his own washing and toilet facilities.
That leaves my daughter, working from home with her SENCO students, and having sole responsibility for their four children (3 x teens, 1 subteen), shopping, cooking, ensuring kids studies are kept up, etc. etc. I am less than a quarter of a mile away, but so reluctant to ask her for anything as she has enough on her plate.
Strange thing was the my SiL was told by GP that he HAD to come in for his blood tests that enable them to continue prescribing certain medication. They did try to arrange it for him before any other patients, but it was the first time he had been out of his room since told to totally self-isolate.