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Astra Zeneca Vaccine

(228 Posts)
maddyone Tue 06-Apr-21 17:11:23

It has been reported recently that there is a link between the Astra Zeneca vaccine and blood clots in young women. The Guardian has reported that Marco Cavaleri, the EMA’s head of vaccines said ‘We can say it now, it is clear there is a link with the vaccine.....’ However Europe’s drug regulator has denied it has already established a causal connection between the AstraZeneca vaccine and a rare blood clotting syndrome.
I’m puzzled. The head of EMA says there’s a clear link, then it’s denied. What is going on?

icanhandthemback Wed 07-Apr-21 14:55:59

Are these particular blood clots which purportedly happen because of the AZ vaccine usually reported to the authorities? I am a little skeptical at their rarity if they aren't. Illnesses which were considered rare historically turn out not to be rare at all but are undiagnosed or the data hasn't been pulled together.
If you look at the MMR vaccine and those that were convinced it caused autism which now seems unsubstantiated, it could be that this is a coincidence. We now know with Autism that children often appear to be perfectly NT initially but then regress and the timing of the MMR just happened to coincide with that.
I reserve judgement about the causes of the blood clots but I certainly don't think it is helpful for people to avoid the AZ vaccine. They should just be vigilant, the same with any medication.

MayBee70 Wed 07-Apr-21 14:35:14

Might that be because women in France tend to smoke? I’m asking that out of complete ignorance and don’t wish to offend any French women. It’s just something that popped into my head.

olddudders Wed 07-Apr-21 14:09:04

A couple of statistics from France. [Yes, another poster has pointed out that the stats I copied over earlier don't add up - I have just checked and they are exactly the same figs on the official French health watchdog site.]

Of the serious side-effects examined, approx only 25% were suffered by male patients - true across all three vaccines. This is not man-flu! OTOH, since the pandemic started, the gender split of deaths in France has been the other way, with 59% of deaths being men. That is really odd, because there are rather more ladies in the very high age-groups that suffered so badly.

Blinko Wed 07-Apr-21 13:44:45

If you're older, like me (74) I really can't see what all the hoo ha is about. The stats, outlined in this thread and elsewhere, speak for themselves. FGS. Get the jab!

maddyone Wed 07-Apr-21 13:38:07

Yes Maybee, I think you’re right. The AZ vaccine does seem to be an ideal candidate to be used in poorer countries. It’s also being sold at cost.

maddyone Wed 07-Apr-21 13:36:18

That was in response to Aveline’s post.

MayBee70 Wed 07-Apr-21 13:35:57

maddyone

I think the Moderna vaccine has been used mainly in America Maybee.

Yes. It was authorised in December. However, as with the Pfizer one it has to be kept at very low temperatures. The AZ one still seems to be the only one that can be easily used in poorer countries. I thought they used it in Brazil last year with no problems?

maddyone Wed 07-Apr-21 13:34:17

Oh dear, I had the virus rather badly. Some three months on I still have regular pain in my lower left lung where the Covid pneumonia was, and occasionally other lung/chest pains. I’m hoping this will gradually heal. I have improved enormously since my discharge from hospital, but it does take time.

MayBee70 Wed 07-Apr-21 13:31:11

Dr John did say ages ago that different vaccines would probably be better for certain age groups. He’s usually right about most things. We’re learning as we go along aren’t we. At the start of the pandemic I would have happily had any vaccine if I thought it would help my children and grandchildren go back to having a normal life so I can’t believe how much has been achieved in such a short space of time. And anywhere that has high infection rates ends up with new, more dangerous variants. We’ve got to keep moving forward.

Aveline Wed 07-Apr-21 13:28:38

BTW I know very well that there is a range of type and potential location of thromboses! These range from relatively common to vanishingly rare.
In other news, research is finding evidence of long term neurological damage post Covid infection and increased risk of psychiatric illness.
More reasons to take the vaccine!!

maddyone Wed 07-Apr-21 13:27:32

I think the Moderna vaccine has been used mainly in America Maybee.

maddyone Wed 07-Apr-21 13:26:28

.....people.........are now happy to have the Moderna vaccine that we know little about.

Very true it seems.

maddyone Wed 07-Apr-21 13:23:55

Good news on the Moderna vaccine today, the first one in Britain has been given to a 28 year old woman in Wales. It’ll be rolled out in the rest of the UK in the next few days. Maybe it could be given to young women in particular. Or would the logistics of that be too difficult?

MayBee70 Wed 07-Apr-21 13:23:45

People are scared to take the AZ vaccine of which millions of people have had with no problems. But are now happy to have the Moderna vaccine that we know little about. Does anyone know how many people have had it? It will be interesting to hear what JVT says this afternoon. They roll him out when they need someone that people trust. There gave been so few cases of these blood clots. They must surely have found some sort of common factor in the people affected other than being young and female. And why more in Germany than here? I feel that we’ve taken two steps forward and one step back. But will still have my second vaccine.

suziewoozie Wed 07-Apr-21 13:19:39

Not his mum but I do have him on speed dial and he’s in one of my WA groups ?

maddyone Wed 07-Apr-21 13:18:19

Kandinsky

I don’t know what the problem is?
Just scrap the AZ vaccine and give people the other vaccines that haven’t been linked to these rare blood clots.

Are you actually being serious? Without the vaccines we would be in total lockdown for the foreseeable future. And there are not enough vaccines available to simply substitute with different vaccines.
Four of my children/in law children have had the AZ vaccine without ill effects, as do the vast majority of people, even when they’re female and below the age of fifty. I’m eagerly looking forward to the other two getting their vaccines, whichever one they’re offered.

suziewoozie Wed 07-Apr-21 13:16:54

Aveline

Contraceptive pills cause blood clots. Should we stop them being prescribed? Long journeys also dangerous for DVTs. Best stop them too. Or, alternatively, get a grip!

You are missing the important point that the blood clots in question are a very specific kind which is why there is ‘concern’.

Alegrias1 Wed 07-Apr-21 13:01:50

suziewoozie

Aveline

Just read that the GN pin up JVT is leading a televised briefing on this topic at 3pm today. Good.

Just what I suggested?

You're not his mum, are you? grin

Johnathan, get on the telly, your country needs you!

Alegrias1 Wed 07-Apr-21 13:00:38

Interesting speaker on the Vanessa Feltz program on Radio 2 just now ( don't judge me wink)

Trying to show the difference between the extremely rare type of blood clot we're talking about with AZ, as Greeneyedgirl said above, and "normal" blood clots that happen all the time. He said that the blood clots we're worried about are so rare that they don't even have data on how likely they are in the normal population without vaccines, and he had a proposal about how the vaccine could be causing the clots. But said over and over again, its still much, much safer to have the vaccine than COVID-19, although that needs to be looked at in the younger cohorts where the risk of Covid is so much lower.

I think the JCVI need to get their act together. Acting "in a personal capacity" when it is such an important thing, is not on.

suziewoozie Wed 07-Apr-21 12:57:43

Aveline

Just read that the GN pin up JVT is leading a televised briefing on this topic at 3pm today. Good.

Just what I suggested?

suziewoozie Wed 07-Apr-21 12:56:31

Whilst I remain critical of JCVI I have sympathy for MHRA ( as I did for the other national regulators who paused because of the blood clot issue). Because we live in a leakey sieve, there was no way it could be kept quiet that MHRA were carrying out an investigation - and part of me thinks it shouldn’t have hidden because that would equally lead to distrust when it came out. But as you say GG the messaging ie communication should have been better handled. Sadly there’ll be some negative effects whatever MHRA rules. In the end it will all come down to balancing the risks won’t it? And luckily there are other vaccines which may be more suitable if necessary.

Aveline Wed 07-Apr-21 12:55:34

Just read that the GN pin up JVT is leading a televised briefing on this topic at 3pm today. Good.

Aveline Wed 07-Apr-21 12:47:47

Contraceptive pills cause blood clots. Should we stop them being prescribed? Long journeys also dangerous for DVTs. Best stop them too. Or, alternatively, get a grip!

GrannyGravy13 Wed 07-Apr-21 12:46:29

Definitely bad communication. How many young women take the contraceptive pill, injection or implant? If you read the information sheet inside any medication (even over the counter products) they have to give you every worse case scenario of possible side effects. The yearly flu jab or any holiday required vaccinations/medications can cause problems.

The risk of dying or having serious long term effects from Covid-19 are still far greater than developing a clot with any of the vaccines.

I am still happy for any of my off-spring to have the second dose of AZ as is my DH who has previous history of TIA and is in medication. I had the Pfizer vaccine and eagerly await my second dose.

suziewoozie Wed 07-Apr-21 12:26:03

When sensible countries like Denmark and Norway paused because of blood clots, many GNers scoffed -now the shoe’s on the other foot and there’s understanding of being cautious and criticism of media reporting. No one seems to have picked up n my point that JCVI are not handling this well either various members giving interviews ‘in a personal capacity’. I also think the whole issue is being communicated badly at the centre.