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Coronavirus

Imperial College Fingerprick test

(30 Posts)
Babs758 Sat 29-May-21 10:49:07

Has anyone in here done this. I did one as part of a research programme 1 week after I had the 2nd AZ vaccine. It was a fingerprick blood test that gives results in 15 minutes. Apparently I have No antibodies! Having been pretty isolated for over a year now and followed all the rules I am pretty upset. Apparently these tests give 80% accuracy. Should I worry? Would appreciate some replies from medical people on here that know more than I do!

Shelflife Sat 29-May-21 10:59:31

Gosh! Not surprised you are upset. Have no medical knowledge to offer you but I feel sure there will be people on GN who will advise you. I wish you the best in this situation. It makes me wonder - like most people I have had my second vaccination and wonder what my results would be if I had the finger tip blood test. Certainly food for thought. I am interested to know how this situation progresses. Best wishes and good luck ?

Babs758 Sat 29-May-21 11:01:25

Thanks!

Omaoma57 Sat 29-May-21 11:03:15

My OH was invited after having both his jabs and he is full to the brim with antibodies.

Alegrias1 Sat 29-May-21 11:03:38

I'm not a medical person smile But there is a video on YouTube by Tim Spector explaining why its not a problem if the test shows you don't have antibodies. I'll try to find it later on, and post it. In the meantime somebody may come along to explain what it is that he's saying. flowers

Whitewavemark2 Sat 29-May-21 11:06:07

T-cells are more important apparently.

Whitewavemark2 Sat 29-May-21 11:06:43

That’s not an explanation btw?. Just me burbling.

Alegrias1 Sat 29-May-21 11:18:04

Here it is:

www.youtube.com/watch?v=tE47JhlV39g

Its right at the start of the video. I don't know if this is valid or not but it seems pretty sensible and he's usually right about things.

Manhattan Sat 29-May-21 11:19:03

After the initial immune response to a vaccine, antibodies will gradually disappear but the Memory B cells created remain. As the name suggests, it is these cells which remember the antigen and trigger an immune response to future infection. A good explanation here:

www.mydr.com.au/travel-health/vaccination-and-antibodies/

Babs758 Sat 29-May-21 11:33:59

Thanks! Both very good explanations. The fortress test I took checks for M ie natural immunity (I apparently don’t have any) but not for the spike results due to the vaccine. The article on T cells is quite reassuring. Thanks both!

Shelflife Sat 29-May-21 11:38:40

Sounds like good news Babs, very reassuring.

Shelflife Sat 29-May-21 11:39:33

GN is amazing !

Babs758 Sat 29-May-21 12:53:47

Yes it is!

Esspee Sat 29-May-21 13:24:08

Babs758

Thanks! Both very good explanations. The fortress test I took checks for M ie natural immunity (I apparently don’t have any) but not for the spike results due to the vaccine. The article on T cells is quite reassuring. Thanks both!

I can’t see how any of us can have natural immunity unless we have been exposed to the virus. It is a completely new virus after all.
You don’t need to worry.

Elegran Sat 29-May-21 13:55:45

If you have been isolated for a year, you will not have come into contact with the virus, so will not have developed natural immunity! Natural is the keyword here. If you have been isolated, you will have developed antibodies, but not as many as if you had caught the virus and had to fight against it.

I took a BioBank rapid Test (they are constructing a database of who has antibodies and who hasn't) I was disappointed to find that the result was negative, after both jabs, but it was explained that there would be enough antibodies stimulated by the vaccine to fight off the virus (or to weaken it at least) but they might not come up to the level that they were testing for. I think my negative result will be in the database, but marked as being after vaccine.

Babs758 Sun 30-May-21 10:39:40

That is very useful. Thanks!

Elegran Sun 30-May-21 10:48:53

I've jst seen a mistake in my post. Instead of "If you have been ISOLATED, you will have developed antibodies but . . " I should have put "If you have been VACCINATED . . " I hope it still made sense?

Manhattan Sun 30-May-21 11:03:18

Esspee

Babs758

Thanks! Both very good explanations. The fortress test I took checks for M ie natural immunity (I apparently don’t have any) but not for the spike results due to the vaccine. The article on T cells is quite reassuring. Thanks both!

I can’t see how any of us can have natural immunity unless we have been exposed to the virus. It is a completely new virus after all.
You don’t need to worry.

From Peter Doshi associate editor of the BMJ:

Not so novel coronavirus:

At least six studies have reported T cell reactivity against SARS-CoV-2 in 20% to 50% of people with no known exposure to the virus.

www.bmj.com/content/370/bmj.m3563

Esspee Mon 31-May-21 07:21:21

Manhattan To me that implies that the people who showed T cell reactivity must have contracted some similar virus previously. Have I got that right?
It doesn't mean some of us are born with inbuilt immunity.

Esspee Mon 31-May-21 07:27:28

Manhattan
To me that implies that the people showing T cell reactivity must have, in the past, had contact with a similar virus.
Not that they were born with natural immunity.
Am I reading that correctly?

Manhattan Tue 01-Jun-21 18:37:17

Yes, Esspee, it does. That seems to be the main thrust of the BMJ article, that this may not a novel coronavirus after all. It'll be very interesting to see what comes of the lab-leak investigations.

www.theguardian.com/commentisfree/2021/jun/01/wuhan-coronavirus-lab-leak-covid-virus-origins-china

Blossoming Tue 01-Jun-21 19:37:16

Great link Manhattan thanks

Esspee Thu 03-Jun-21 11:22:41

Manhattan
Do you feel that if this is the case, i.e. that we have weathered this virus before (presumably under the “flu” banner) that this world reaction, or should I say overreaction? is unwarranted?

M0nica Thu 03-Jun-21 12:07:53

I did a similar test and the instructions made it absolutely clear that no antibody line was nothing to worry about.

My test produced a barely visible line, so faint, it was very difficult to see, unless I looked at it ia a very good light, can't say this bothered me at all. I have had my jabs and I assume they worked because the 'failure' rate, if any is infinitely small.

M0nica Thu 03-Jun-21 12:23:32

Thank you for that article Manhattan. It has been added to my copy and save file, along with a numbe of others.

The lesson I learn from it, is that no theory, no idea should be taken to excess. In human terms, most people love cream cakes. An occasional cream cake is fine and dandy and enjoyable. Eat too many and you grow fat and unhealthy.

There is one thing the author said that I would add to. Discussing the Lab-escape theory of corona virus he says:

Could a world full of scientists do all kinds of reckless recombinant things with viral diseases for many years and successfully avoid a serious outbreak? The hypothesis was that, yes, it was doable. The risk was worth taking. There would be no pandemic.

I would add that the Chernobyl nuclear accident was also caused by scientists thinking they could do reckless experiments and avoid a serious nuclear event. The hypothesis was that, yes, it was doable. The risk was worth taking. There would be no nuclear meltdown.

Bears thinking about.