Post natal depression springs to mind. I have no experience of this so obviously may be completely wrong! Although it does seem strange that in the past you have had a sound relationship. Or perhaps not as sound as you thought? Is it possible your desire to help has been a bit overwhelming for your DIL and she needs you to back off a little, even though you had nothing but good intentions. Your son is naturally protecting and standing up for his wife. He too may be under great stress especially if there is a post natal problem. How about an email, or old fashioned letter may be more to personal. Tell him the basic facts , ie how concerned you are for your DIL. I wouldn't broach the subject of possible PND . or the fact that you miss your GS. Simply make it clear how worried you are This might be a gentle approach that may encourage your son to communicate. Whatever happens please don't fall into the trap of making it about you and how much you miss your GS and former relationship with your DIL. It is an easy thing to do when you feel so upset! As for not having as much contact with your GS , please don't stress about that- lots of time to re connect when this rocky road is over.