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Dangers of NSAIDs?

(40 Posts)
Rowantree Fri 02-May-14 10:37:20

I recently read something in the Grauniad (the second section, the column written by a GP) about taking drugs such as Ibuprofen. I can't find the article now but I seem to recall there were dangers such as heart attack or stroke when taking high doses. I am rather worried about this - when I have symptoms of cystitis I take a largeish dose or two (as advised on the pack, nothing over and above) because it helps with the inflammation as the d-mannose or the antibiotic takes effect. I also take it for headaches sometimes. Has anyone else read anything worrying about NSAIDs? I know that every drug has side-effects, but I'm particularly worried about stroke/heart attack as I'm very overweight and trying to come off antidepressants because they made this problem worse.
If it's not one thing, it's 'tother! I'd like to know/read a balanced evidence-based study about it though.

janeainsworth Sun 11-May-14 13:31:31

FLEXISEQ does not contain any pharmaceutical drug, and consequently FLEXISEQ benefits from an excellent safety profile

Haha. They would say that, wouldn't theygrin

Brendawymms Sun 11-May-14 13:46:02

I take the maximine dose of a NSAID but recently have to top it up with co-proximal and the last two days this has had no effect at all. In fact for a few minutes thought of going to A & E but could not stand to have to be there to be told to take painkillers. Getting older is no fun.

TriciaF Sun 11-May-14 13:52:18

I never take ibuprofen because it upsets my stomach. And anyway I have a heart problem so it's supposed to be interdit. I'm not sure what the connection is, maybe clashes with all the other things I have to take.
But it does wonders for some conditions - husband takes Nurofen (similar) for sciatica and it really helps.

Aka Sun 11-May-14 14:01:56

If Arthritis UK are backing it I might give it a try, after all nothing ventured...

Galen Sun 11-May-14 14:18:06

Brendawymms
Co-proxamol was banned several years ago. How on earth are you getting it?
It's a pity actually as it was an excellent pain reliever.
I gather too many people committed duicide with it!

Galen Sun 11-May-14 14:18:35

Duicide? Suicide!

Brendawymms Sun 11-May-14 14:32:40

Probably bought it over the counter aboard. Like in this country, even in a pharmacist, you are limited as to how much paracetamol you can buy. In Australia and New Zealand you can buy 100 packets. I know how addictive etc medication can be but at times I make the decision that I would sooner have less pain and only take it on really rare occasions.

Brendawymms Sun 11-May-14 14:34:54

Also meant co-codamol not co-proximal.

Galen Sun 11-May-14 14:35:29

It's the only thing that stopped my pain when it's bad. Only have paracetamol now as I don't like co codamol!

rosequartz Sun 11-May-14 14:38:43

I was prescribed co-codamol for a rotor cuff injury but it made me spaced out.

JessM Sun 11-May-14 18:21:45

I noticed that gem Janeainsworth - possibly the kind of rub in gel that does contain pain killers might be a better bet?
Flexiseq does claim to contain little lipid globs that go in through your skin though. Perhaps if you have time you could decipher the ingredients list on the patient leaflet. I got as far as water, glycerine and salt...

Iam64 Sun 11-May-14 19:25:04

I had a bone density scan last year, hips in osteo pina range (that's the one before osteo porosis). It was part of the general care for patients with inflammatory arthritis (we're more prone to osteo arthritis, the joys eh folks). So, my gp prescribes calcium, and recommended i take glucosoman and chondriotin (sorry, I'm sure Galen and others will spell that properly)
The hope is the calcium treatment will return my hips to a better density level.
My GP used to prescribe gluco/chondri but prescriptions for this were stopped some years ago, as the research didn't support continuing to prescribe. I've been taking it again for 3 months, and it may be coincidental, but I'm not needing anti inflammatories so often, and the pain levels in my hands/feet/knees/hips have reduced. My memory is I felt better when taking it in the past, but had concluded that the increase pain etc was down to ageing. Anyway - on the cheerful note that something is helping, I'm off. good luck to everyone managing to live their lives with chronic pain and poor mobility. And! I regret that suicides led to coproximol being banned. I found it more effective, and with less side effects than cocodomol has.

Aka Sun 11-May-14 19:35:40

Iam64 have you read any of the research on Vit k2 as menaquinone and bone density?

Iam64 Mon 12-May-14 07:28:40

not yet Aka, but I will google it, thank you