I have done several home screenings and they have all come back negative. I ended up having a colonoscopy last week as a result of going to the docs with lower back pain and concerns that it might have been caused by a prolapsed bowel. In fact, it was not, but after asking a lot of questions, she sent me to the hospital anyway on a two week referral, which I have posted about elsewhere on the forum. Given the number of these procedures they carry out every week, and the number of lives they save, the benefits must outweigh the risks. The chances of a perforation if no polyps are removed is less than one in a thousand. About half that if polyps are removed. A colonoscopy can pick up smaller anomalies than the barium enema procedure, which is cumbersome and lengthy. I have had both. Camera technology is amazing. My niece recently had two chest x-Ray's for a lung complaint. Both came back clear. She was not convinced that there was not a problem and insisted on a bronchoscopy, which picked up a tiny malignant tumour. Because it was small, it had not spread, and the surgeon managed to get all of it with surrounding tissue and she can go back to living her life again. He said that it was so small it would never have been picked up by any other means. I was told that my results were clear, with no biopsies taken. I know that others have not been that lucky and I genuinely feel for them. I think that women are much better at taking responsibility for their health than men. I have to hold a gun to DH's head to get him to see the doctor if I suspect that he has a problem.