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Omeprazole v Ranitidine

(21 Posts)
Katek Fri 17-May-19 10:16:16

For various reasons I have had my hiatus hernia medication changed from Omeprazole to Ranitidine and it is definitely not working as well. I’m having to supplement the Ranitidine with doses of Gaviscon in order to control symptoms. Has anybody else had a similar experience with this change of meds? Omeprazole kept things well under control for 20 years but I almost feel as if the Ranitidine is barely having any effect as I’m experiencing symptoms I’ve never had before. I follow all the dietary guidelines but any other handy hints much appreciated!

jaylucy Fri 17-May-19 10:26:06

I have a hiatus hernia and have taken Omeprazole and am currently on Ranitidine. The main reason I was given is that Omeprazole can inhibit some other drugs (such as certain ones for HBP from working as they should)
Where I used to take Omeprazole in the morning, I take Ranitidine in the evening, at least an hour before bed and it seems to work - unless I have eaten later in the evening than usual!
I'd suggest that you go back to your GP and explain the problems you are having and you may either have the dosage adjusted or back to Omeprazole.

Farmor15 Fri 17-May-19 10:34:43

What dose of Ranitidine do you take? Some of the versions on sale are only 75 mg which may not do much. I have a hiatus hernia and take Ranitidine - 150 mg, as I need it. I also take one of the "prazoles" (ppi's - omeprazole, pantoprazole etc) now and then, especially if I know I'll be going out and less in control of what I eat and drink. I also always carry Rennies with me - in pocket of every coat, handbag, by the bed!

Ranitidine has a much shorter effect than Omeprazole - less than 12 hours, but my experience is that it starts working faster, usually after about 1/2 hour. As far as I know, it's ok to take 150 mg every 12 hours. It has fewer side effects than Omeprazole. Long term use of ppi's is now known to have various risks, which is why you may have been taken off it, but using now and then is OK.

I often take a ranitidine shortly after a meal and before I do something like gardening, which will involve bending down - very bad for someone with hiatus hernia! I also avoid eating late, or big meals. I do supplement with Rennies, as needed, but since they are a source of calcium I reckon they're probably good for bones!

annodomini Fri 17-May-19 10:37:42

I have both. The ENT consultant who diagnosed laryngo-pharyngeal reflux prescribed them along with Gaviscon Advance. Sledgehammer approach? I have tried missing out one or the other and found my voice deteriorating again.

Gonegirl Fri 17-May-19 10:55:49

I am on 20mgs omeprazole which I have recently been taking in the evening . (trying to avoid bad nights with reflux.) It's not really doing the trick though. Had a miserable night last night. Perhaps I will add some Ranitidine alongside the Omeprazole. You can buy it cheap as chips. The dosage on the package states 75 mgs but 150 sounds more realistic.

Farmor15 Fri 17-May-19 12:40:15

Gonegirl - from my experience omeprazole takes longer to "kick-in" than Ranitidine. If I take it, it's early in the day, best before eating, whereas Ranitidine takes effect pretty fast. If I have any symptoms, I take one about half hour before bed.

It's even cheaper abroad - my OH is from India and we or some family members go fairly often and always bring back a supply of Ranitidine. Standard dose there is 150 mg and it costs about 30p for a pack of 30!

Gonegirl Fri 17-May-19 12:42:42

Wow - that's very good. Cheaper than Tesco.

fizzers Fri 17-May-19 14:38:18

I currently take Lansoprazole (have had omeprazole in the past) can also take ranitidine 150 mg and/or Gaviscon, TBH am currently not happy with any of the medications but do find Lansoprazole with Gaviscon works the best

Fennel Fri 17-May-19 15:22:10

This is interesting for me because I have groin hernias (not hiatus) and am trying Lansoprazole. It doesn't help much.

Katek Fri 17-May-19 22:50:14

I was on 20mg Omeprazole and now on 150mg Ranitidine twice daily. I’m having to back this up with Gaviscon Advance or Rennies but I’m still plagued with pain and reflux. Going back onto Omeprazole isn’t possible in my case, so I’m at a bit of a loss as to what to do. I never had any issues whatsoever on Omeprazole so I’m finding my current problems more than a little annoying! I’ve also developed a complete intolerance to cooked cheese-so lasagne, macaroni cheese etc are now off limits. I can still eat a cheese sandwich so not sure what happens to alter the digestibility of the cheese when it’s cooked.

Culag Fri 17-May-19 23:47:34

Like annodomini, I have laryngo-pharyngeal reflux due to a hiatus hernia. I take 300mg of Ranitidine at night along with Gaviscon Advance liquid and tablets, and Omeprazole in the morning. If I stop the omeprazole I get a sore throat. Fortunately I find that it makes no difference as to what I eat ?.

lemongrove Sat 18-May-19 08:53:31

Omeprazole has changed my life...for the better, I can’t think of life without it.
Talk to your GP katek as you don’t want to feel worse than you did.

vivonce Sat 01-Jun-19 12:05:26

Unfortunately I have had bad experiences with both. I was on Ranitidine for many years and thought I was fine. But just over a year ago I had a series of blood tests - the original reason being a process of diagnosis and the outcome being the onset of Fibromyalgia. But along the way, the Vitamin D count tested 'dangerously deficient.'
The shocking deficiency was treated by prescribing the vitamin big-time, but the dr also changed my antacid to Omeprazole while fairly silent about reasons.
While googling I found reams of info re. the fact Ranititine depletes the body of its Vitamin D. Alarming!

The Omeprazole however, is not successful and it is advisable to read the little leaflets in the box, where it says '1 in 10/100/1000 may experience X symptoms'. It seems I am 1 in 100 to have severe night-time sweats! I have had to buy new pillows and throw away fairly new drenched ones. The Dr reduced my dose from 20 to 10 mgs but it
still happens. Much worse than menopause sweats 25 years ago.
So now I am taking them only 2 or three times a week, so of course, heartburn still occurs. I can't take Gaviscon so Rennies are used. Btw, the new over-the-counter Nexium Control is also Omeprazole.

Gonegirl Sat 01-Jun-19 13:08:40

Katek you need to find out why the doc took you off Omeprazole and put you on Ranitidine. Ranitidine is not nearly as effective. Definitely go back and in the meantime I would buy some online.

Gonegirl Sat 01-Jun-19 13:09:47

these people are good

dragonfly46 Sat 01-Jun-19 13:13:35

I am always wary of buying prescription drugs online. I take Lansoprazole and find it works well but I have read that you must not take any other drugs within 2 hours.

Gonegirl Sat 01-Jun-19 13:16:59

You're alright so long as they've got the two 'verifying' symbols.

Greyduster Sat 01-Jun-19 13:17:54

I took Omeprazole for some years and then it stopped working. I was put on Lamsoprazole, which gave me diarrhoea, so was switched to Ranitidine 150mg which works fine most of the time. When it doesn’t I take a dose of Gaviscon alongside it. I get the impression we have run out of options now!

Katek Sat 01-Jun-19 13:20:57

I already know gonegirl, my QT interval on a routine ECG was lengthened and Omeprazole is the culprit it would appear. Long QT intervals can cause significant arrhythmias and even worse. My QT interval is now back to normal but I am not doing nearly as well on Ranitidine. My whole digestive system from one end to the other is not functioning well at all. I have appointment with gastroenterologist on Tuesday so I’m hoping (praying!) he can identify a better way forward. There is a whole list of medications which may cause this from some antibiotics to bp meds. Will try and find link but it’s sonething to be aware of.

FC61 Sat 01-Jun-19 13:24:09

Can anyone describe the symptoms ? Is it a feeling you’re hungry even if you’ve eaten ? Or is there a horrible fluttering when you’re hungry ? I was put on omeprazole and it was awful because I didn’t digest anything. So I’m not sure I have a problem although a hiatus hernia was vaguely suggested one.

Katek Sat 01-Jun-19 13:24:57

This gives a fairly comprehensive list of meds which can cause elongated QT

crediblemeds.org/pdftemp/pdf/CombinedList.pdf