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Amlodipine possibly helps to slow or prevent dementia.

(31 Posts)
shysal Thu 16-Sept-21 09:59:30

www.msn.com/en-gb/health/mindandbody/high-blood-pressure-drug-could-be-re-purposed-to-tackle-dementia/ar-AAOtOm1?ocid=msedgntp
Interesting article popped upon my home screen this morning.
I take 5mg daily with no side effects, so I am pleased that there might be another benefit. Anyone else take it?

annodomini Thu 30-Sept-21 10:43:31

Oh well, Nanna58. Another hope dashed. shock. I'm so sorry about your mum. It must be hard for all her family.

Caleo Thu 30-Sept-21 10:34:00

My legs and feet swelled possibly due to daily 5mgs Amlodipine I had to get new shoes and sandals and can't wear boots.

Nanna58 Thu 30-Sept-21 10:19:13

Sorry, but Mother has been on it for years and has advanced Dementia. ?

goose1964 Thu 30-Sept-21 10:12:37

I'm on it as a cocktail of meds for my blood pressure. My gran had vascular dementia so I'm hoping this will work

Whiff Thu 30-Sept-21 10:08:50

I had been taking 5mg of Amlodipine once a day for years. Was diagnosed with AF the Saturday before bank holiday. First thing they did at AF clinic was take me off it because of water retention. Never had any problems with it apart from swollen ankles before getting AF. But apparently AF and Amlodipine is a bad mix.

PinkCakes Wed 29-Sept-21 18:44:33

I was prescribed Amlodipine in July, took them for a month but my feet and legs swelled up to just below the knee. The GP changed them to Lercanidipne, and they seem to suit me better.

Riverwalk Wed 29-Sept-21 11:26:52

Do you have any links for that Kali? I'm always sceptical about claims for turmeric - particularly as there is no recommended dose.

I use it in cooking!

Kali2 Wed 29-Sept-21 10:20:46

Serious research studies have also shown great results with Turmeric- which is cheap and easy to get.

MiniMoon Wed 29-Sept-21 10:19:13

I gave out bucket loads of amlodipine when I worked in a nursing home for people with dementia. I think its a lottery really. I hope the study is accurate, but I'm taking it with a pinch of salt.

shysal Wed 29-Sept-21 10:06:15

Granny23

Sorry to report that my DH was on Amlodipine for years but latterly succumbed to Dementia. Perhaps it depends on which type of Dementia you develop? His was Frontotemporal.

I think the possible success is linked to vascular dementia

BlueSky Wed 29-Sept-21 09:54:35

I tolerate the 5mg but not the 10mg which gives me bad palpitations, also I occasionally get hot flushes (well past the menopause) and the GP agreed it’s the Amlodipine. But it helps managing my BP.
Granny23 sorry to hear about your DH, it may help preventing dementia but sadly won’t be for everybody.

Trisha57 Wed 29-Sept-21 09:08:57

I've been on 10mg for nearly 10 years with no apparent side effects. Good to hear that it may have side benefits. BTW, seeing this thread reminded me that I hadn't taken my tablets yet - can we start a "Have you taken your tablets today?" thread to remind me every morning?!!!

Granny23 Wed 29-Sept-21 09:08:20

Sorry to report that my DH was on Amlodipine for years but latterly succumbed to Dementia. Perhaps it depends on which type of Dementia you develop? His was Frontotemporal.

Hetty58 Wed 29-Sept-21 08:51:39

I know people who've taken it for years - as it seems to be the first thing prescribed for HBP (probably the cheapest too).

I couldn't tolerate it at all. I had a splitting headache, dizziness, nausea, sickness - and complete loss of balance!

Shrub Wed 29-Sept-21 08:41:23

That’s the second bit of good news this morning! I wonder if there’s going to be a third?

Riverwalk Wed 29-Sept-21 08:28:57

I've been on it for about 10 years and have very nice ankles!

Good news about dementia smile

Oopsadaisy1 Wed 29-Sept-21 08:17:54

I started taking them 3 weeks ago for high BP, they seem to be working and no ‘Kankles’ yet!

maddyone Thu 16-Sept-21 10:45:53

I take 10mg a day. I started on 5mg but after a year it didn’t control my blood pressure so the dose was raised and has worked well ever since. My husband also takes Amlodipine. We don’t suffer from swollen ankles normally, but I do find they swell when I’m walking a lot on holiday and the weather is very hot.
It’s good news to hear it’s probably got other benefits, but I understand the study was on mice and is now to be conducted with humans.

BlueSky Thu 16-Sept-21 10:45:10

Well some good news about medication instead of the usual doom and gloom ones! I take 5mg Amlodipine with other tablets and I do need this specific one to stop by BP from going sky high. So if it helps with dementia, all the better!

annodomini Thu 16-Sept-21 10:32:06

I take it too. My GP told me it might cause my ankles to swell and I could also have hot flushes. I used to be quite proud of my slim ankles, but sadly they are puffy nowadays. I do also have hot flushes, but not for long and not always. If it is really proven to delay the onset of dementia, I will live with puffy ankles and the odd hot flush.

crazyH Thu 16-Sept-21 10:10:23

????? dr started me on 10mg but it made my feet swell - reduced it to 5 mg and fine since then….

Blossoming Thu 16-Sept-21 10:07:30

I’ve been taking 5mg amlodipine for almost 20 years, so that’s very good news!

henetha Thu 16-Sept-21 10:07:24

Wow. That's brilliant news. I've been on it for several years now, obviously for high blood pressure and it works. I've never had side effects. So if it keeps dementia at bay too, that is fantastic.

tanith Thu 16-Sept-21 10:06:51

I had very swollen ankles when i took it for a few days sadly.

ExDancer Thu 16-Sept-21 10:04:46

It made my legs swell so much I literally couldn't wear any of my shoes.