For me, voting Leave had nothing to do with party politics. It was to do with sovereignty both in 1975 and 2016. For my friends and family, who are split, it was not related to party politics.
Of course, we had a Referendum because of party politics but the Second Reading of the Bill passed with a thumping majority with only SNP as a party objecting. Labour, having campaigned against a Referendum, supported the Referendum Bill. Sadly, no MP that I could find, whether Leave or Remain, suggested that preparations should be made for either outcome before the vote. Given the level of euro-scepticism in the country from the 1960's onwards, and particularly after the Credit crunch, one would have thought this an imperative.
The Leave vote was 53.4% in England, spread over much of the country, highest in the Midlands, North and East of England. The highest Remain area was Scotland where, nevertheless, 38% voted Leave.
If there was a particular economic factor affecting the vote, I suspect it was The Credit Crunch in 2008. There were, though, many reasons why people voted Leave (as with Remain voters) but ultimately, we were only given the choice: to Leave or Remain in the EU.
In Italy, the new coalition which is causing concern in Brussels and in bond markets, perhaps also had its roots in the Crunch and the reported fact that ever since joining the euro, Italy's average growth has been zero.