I think the son had problems getting furloughed, so presumably has no income?
What would you like to do, Skysearcher? At 66, you have more than earned the right to retire if you want to, and shouldn't feel guilty for doing so. Do your son and daughter get benefits or other income? Is your daughter able to work?
Either way, as adults they should be supporting themselves, even if you help out now and then when they need it.
I know we never stop being mothers, and always want to help our children, but I can't help thinking that it's time for you now.
Maybe give your daughter a deadline by which she needs to find a job and contribute to your budget, or find somewhere of her own to live (whichever would work best for you).
Do you have a partner living with you? Are they contributing financially, or is all the responsibility yours? It doesn't seem fair that you should be propping up so many people, particularly as you have health issues. I think it's time for some straight talking, but you need to be prepared to stick to your guns.