I couldn't care less, but it feels like a step back from Izzard's previous claim that he wasn't a transvestite, just a man in a dress. That was a brave step at the time, and a refreshing statement about gender roles being imposed and non-compulsory.
This seems to play into the hands of those who accept gender stereotypes and want everyone to conform to them by transitioning or declaring non-binary status, as opposed to being themselves and pleasing themselves about what they wear and how they present themselves to others.
What Izzard does would be nobody else's business if there hadn't been this declaration before, and if there hadn't been a contradictory one now. It's been pushed under the nose of the media, so it's inevitably going to get debated, which again goes against the previous message that none of this matters.