It is not normal behaviour for a twelve year old to be rude to adults, in his house and elsewhere; that is simply an excuse. Every child is capable of learning good manners. The problems lie with the parents because they tolerate his poor behaviour, and as they allowed him to treat his aunt with contempt in his own home it is likely he will do the same thing again. She is already dreading the visit and that is not right.
She and her husband need to make it clear immediately, should he be rude, that his behaviour is not acceptable; say so firmly, then leave the parents alone to deal with him. It may result in them leaving, but so what? Attempting to accommodate oafish behaviour only makes it worse, as his aunt discovered.
Good Morning Tuesday 23rd April St Georges Day