Patsie, I read your post as concerns about how differing opinions spoil a friendship.
My sister-in-law and her partner are refusing vaccinations because they don't trust the information we have been given: I do trust it, and both DH and I have been vaccinated (once!)
They think we should have stayed in the EU: DH and I voted to leave.
DSIL and I have very different political and religious views.
We are very good friends and have interesting telephone calls about various situations, and we have supported each during some incredibly difficult times over the past few years, not least when our respective partners have been suffering life-threatening health conditions. Hopefully, I will be able to see her again once we are allowed to travel to EU countries or vice versa! (DH does not like travelling abroad!!)
My ex-daughter-in-law and I have remained good friends despite differences of opinion. In fact, since her own mother died suddenly as the result of a car accident, she seems to regard me as a surrogate mother as well as a friend!
In my experience, friendship is based on love, not on opinions. If you don't feel safe in her company, then talk about it. Keep lines of communication open!
Or have I just been very lucky in my friendships?!!