Who is the first person on GN to get vaccinated?

Mimi22 Alegrias knows very well what she is talking about when it comes to vaccines and scare stories going around.

Mimi22

felice, I am saddened to hear that you are nervous. I wonder what it is that you are actually worried about. The fear has been ramped up to such a degree that logical thinking is over powered. Everyone is doing what makes the most sense to them at the time. It only becomes an issue when you want someone else to do/think what you want/believe in. I believe that the vaccination will do far more harm than good and simply cannot understand why anyone in their right mind would voluntarily stand in line to be injected. Seems like the majority here have the opposing view and can't wait. In means nothing other then we think differently. I have no wish to have others think what I think, or for me to think like them. It's a non-issue and life goes on. If you take away whatever it is that other parents are doing/not doing in the playground is there anything else that leaves you feeling anxious at pick-up?

Where's your evidence that the vaccine (or any of the others) will do more harm than good? What kind of harm do you believe it's going to do?

In what way is the vaccine a toxin? Do you actually know how it works?

Jane10

Mimi22 Alegrias knows very well what she is talking about when it comes to vaccines and scare stories going around.

Thank you Jane10

Yes, I'd like to hear exactly what the harm is that the vaccine will do? Which ingredient (of what is in there, not what you have heard is in a different vaccine) How do you think the vaccine works? How do you think your immune system works? (A clue - it helps your body how to deal with specific potential attackers - the CoVid virus is a potential attacker, which the immune system can't defend you against until it has met it and sussed out what will defeat it)

What is used to preserve the vaccine in its little jar and to stop it growing fungus?
I remember JVT saying something along the lines of it isn't like a yogurt that you could take out of the fridge multiple times.
So what ingredient stops it getting bacterial contamination?

Ellianne

What is used to preserve the vaccine in its little jar and to stop it growing fungus?
I remember JVT saying something along the lines of it isn't like a yogurt that you could take out of the fridge multiple times.
So what ingredient stops it getting bacterial contamination?

I could ask my daughter, but at a guess would it be some sort of alcohol?

My FIL has a date for his 23 dec

My guess is that the vaccine is dry ice, which is CO2 in its solid form. I doubt if bacteria can survive at -70 (or whatever it is).

Ooops! I meant the vaccine is in dry ice. I wouldn't like to be injected with dry ice!!

When will I be vaccinated?
The order in which people will be offered the vaccine is based on advice from the Joint Committee on Vaccination and Immunisation (JCVI).

The NHS will let you know when it's your turn to have the vaccine. It is important NOT to contact the NHS for a vaccination before then.

Further information on why you may need to wait for the vaccine (pdf, 348 KB).

Vaccine safety
The vaccine approved for use in the UK was developed by Pfizer/BioNTech.

It has met strict standards of safety, quality and effectiveness set out by the independent Medicines and Healthcare products Regulatory Agency (MHRA).

Any coronavirus vaccine that is approved must go through all the clinical trials and safety checks all other licensed medicines go through. The MHRA follows international standards of safety.

Other vaccines are being developed. They will only be available on the NHS once they have been thoroughly tested to make sure they are safe and effective.

So far, thousands of people have been given a COVID-19 vaccine and no serious side effects or complications have been reported.

Find out more about regulatory approval of the vaccine.

My guess is that it doesn't need a preservative because of the -70 deg storage, like growstuff says. Also it will have been prepared in a sterile environment so doesn't need to have anything in it to prevent bacterial growth.

This is quite good: www.technologyreview.com/2020/12/09/1013538/what-are-the-ingredients-of-pfizers-covid-19-vaccine/

It says specifically that there is no preservative, and it explains what all the other ingredients are for as well.

I found something that explained that the mRNA was unstable at room temperature, in light and when moved, and will start to break down if exposed to too much of any of this.

Would be interesting to hear what your daughter says WWM

Pap67

Due mine in a few days. I work in healthcare. I’m exited to receive it.

Looks like Pap67 might win the prize!

Alegrias2

My guess is that it doesn't need a preservative because of the -70 deg storage, like growstuff says. Also it will have been prepared in a sterile environment so doesn't need to have anything in it to prevent bacterial growth.

This is quite good: www.technologyreview.com/2020/12/09/1013538/what-are-the-ingredients-of-pfizers-covid-19-vaccine/

It says specifically that there is no preservative, and it explains what all the other ingredients are for as well.

I found something that explained that the mRNA was unstable at room temperature, in light and when moved, and will start to break down if exposed to too much of any of this.

Would be interesting to hear what your daughter says WWM

I’ll ask her. But what about other vaccines?

I think they should publicise the "no thimerosal" so as to reassure those who are concerned about the effects of that (although there don't seem to be any bad effects proved for thimerosal)

oh, lets all hold fire while WWM asks her daughter!! What??

for goodness sake!

Thank you. It was the yoghurt analogy (NOT) that got me thinking.

I rather fancy the idea of an alcoholic yoghurt as a suggested preservative!

I'm not holding fire. I'll get it tomorrow if they phone me. Or even tonight, actually.

I'm just interested and happy to find stuff out from somebody who knows more than me.

Actually thinking about what she has said in the past -although she may say different - I do know that drugs are produced in ultra clean environments, and they are audited for this on a very regular basis.

If any bacteria gets into a production, the whole thing is trashed ultra cleaned and started again.

That’s very simplistic, but hopefully DD will reply with proper information.

Well slap your hand alegrais????

I'm not sure what that means WWM but there are smiley faces so I think its good! ???

In reply to lemsip who seemed irritated?. It may be the weather

Aha!! Got it.....me being thick

The reason you can't keep opening the dry ice containers is that dry ice sublimates in air quite quickly and converts back to its gaseous form, so the temperature in the containers rises, which presumably spoils the vaccine.

Dry ice is nothing to worry about and is commonly used to keep food cool and fresh in transport.

The yoghurt analogy doesn't work if you keep on taking it out of the fridge and bringing it up to room temperature because bacteria will reproduce to an unacceptable level. JVT was making the point that the vaccine can't be taken out of its container and then put back, not because of bacteria or fungi.

Reply from DD

“There are a number of sterilisation techniques. I don’t know what Pfizer use specifically. They can use irradiation, filtration or autoclaving (pressure and heat). Whichever technique or combination of techniques they use will be validated to ensure the product is sterile at the point of administration.

If, in the extremely unlike situation at a bacterium gets through, most people can tolerate a very low level of bacteria entering the blood stream. There are white blood cells that deal with this.”