I too think this is an unreasonable request - have they ever offered to take you on holiday with them or pay for you to have a weekend break away? Probably not I would guess - why do so many of our children have large families then expect their parents to pick up the reins when they want a break? Asking if it is possible is different to demanding it as a right. I look after my three eldest grandchildren as my daughter is a single parent (not her choice, ex son in law walked out on them twice) and works full time. I find it tiring even though we have a routine (of sorts) and when she was away with work for a week recently I was absolutely shattered when she got back, not just because of the physical work of cooking/cleaning/caring for them but also the worry of dealing with illness (both granddaughters were ill whilst she was away) and injuries (grandson can fall over a feather and, at 13, is well into the teenage 'it's not fair' stage if told No). Where are the other grandparents and parents?? Could the children not be sent to stay with the relevant GP/P if they really need a regular break? Keep saying No would be my advice if you can, but perhaps offer a once or twice a year weekend if you feel up to it instead?